Table 2.
Expression of miRNAs in CRCs
| miRNA | Combined (N=345) FCa,b (Q1-Q3)c |
Blacks (N=106) FCa,b (Q1-Q3)c |
Whites (N=239) FCa,b (Q1-Q3)c |
|---|---|---|---|
| miR-20a | 2.05 (0.72–7.31) |
4.14 (1.51–27.3) |
1.60 (0.61–4.78) |
| miR-21 | 2.10 (0.92–5.38) |
3.79 (0.85–11.2) |
2.03 (1.00–4.10) |
| miR-106a | 2.00 (0.61–8.14) |
4.33 (1.06–47.5) |
1.58 (0.58–4.58) |
| miR-181b | 1.33 (0.59–3.97) |
3.97 (0.68–22.8) |
1.06 (0.58–2.34) |
| miR-203 | 2.10 (0.40–9.06) |
5.98 (0.69–71.5) |
1.49 (0.38–5.70) |
N, total number of cases; FC, fold change.
Threshold cycle (CT) is the unit of measurement in qRT-PCR to measure relative gene expression. Difference in CT (ΔΔ CT) = Tumor change in Ct minus paired non-tumor change in CT.
Fold change calculated from ΔΔCt, where fold change = 2-(median ΔΔ CT). Median fold change values are represented.
Q1 and Q3 for inter-quartile range of fold change values.