Table 5.
Cox multivariate regression analysis to evaluate the independent prognostic value of miR-181b in the combined test and validation cohorts of Black Stage III CRCs (N=70)
| Prognostic variables | Indicator of poor prognosis |
aHazard ratio 95% (CI) |
bP-value |
|---|---|---|---|
| miRNA | |||
| miR-181b | High expression | 1.94 (1.03–3.67) | 0.043 |
| Tumor grade | |||
| High vs. low | High | 1.89 (0.91–3.91) | 0.092 |
a
Adjusted for miRNA expression levels, age, gender, TNM stage, tumor location within the colorectum, tumor grade, and tumor size; CI, confidence interval.
b
Adjustment for multiple comparisons has been made for the P values using the Benjamini-Hochberg method.