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. Author manuscript; available in PMC: 2013 Aug 19.
Published in final edited form as: Leukemia. 2011 May 13;25(8):1370–1374. doi: 10.1038/leu.2011.98

Figure 2. Change of Oct-4 promoter methylation and genomic imprinting in VSELs from 6 month old male normal and bGH transgenic mice.

Figure 2

(A) Bisulfite-sequencing results of DNA methylation of the Oct4 promoter in VSELs isolated from 6 month old normal and bGH transgenic mice (bGH). Methylated and unmethylated CpG sites are shown in filled and open circles, respectively. The numbers indicated below bisulfite-sequencing profiles presents the percentage of methylated CpG sites. Bisulfite sequencing results of DNA methylation of DMR for H19-Igf2 (B) and Rasgrf1 (C) loci in VSELs isolated from 6 month old normal and b-GH transgenic mice (bGH). Methylated and unmethylated CpG sites are shown in filled and open circles, respectively. The numbers indicated below bisulfite-sequencing profiles presents the percentage of methylated CpG sites.