Table 1. Comparison of biologically equivalent doses (BEDs) as total doses at 2 Gy per fraction for different dose fractionation regimens.
Dose schedule | BED10 (early responding tissues) | BED1.5 (late responding tissue/prostate cancer) |
EBRT alone schedule (hypofractionation) | ||
55 Gy in 20 daily fractions | 70.1 | 155.8 |
EBRT+HDR brachytherapy boost | ||
44 Gy in 22 daily fractions | 52.8 | 102.7 |
17 Gy in two fractions | 31.5 | 113.3 |
Total dose | 84.3 | 216.0 |
EBRT alone schedule (conventional) | ||
74 Gy in 37 daily fractions | 87.3 | 162.8 |
EBRT, external beam radiation therapy; HDR, high dose rate.