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. 2012 Nov;85(Spec Iss 1):S18–S27. doi: 10.1259/bjr/15403217

Table 1. Comparison of biologically equivalent doses (BEDs) as total doses at 2 Gy per fraction for different dose fractionation regimens.

Dose schedule BED10 (early responding tissues) BED1.5 (late responding tissue/prostate cancer)
EBRT alone schedule (hypofractionation)
55 Gy in 20 daily fractions 70.1 155.8
EBRT+HDR brachytherapy boost
44 Gy in 22 daily fractions 52.8 102.7
17 Gy in two fractions 31.5 113.3
Total dose 84.3 216.0
EBRT alone schedule (conventional)
74 Gy in 37 daily fractions 87.3 162.8

EBRT, external beam radiation therapy; HDR, high dose rate.