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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Eur J Neurosci. 2013 Jan 8;37(6):10.1111/ejn.12113. doi: 10.1111/ejn.12113

Fig. 6.

Fig. 6

NAc dopamine D2 autoreceptor activity in group-housed (GH) and socially isolated (SI) reared rats. Electrically stimulated dopamine overflow was measured while bath-applying increasing concentrations of the D2-type dopamine receptor agonist quinpirole (10 nm–1 μm). (A) Mean μm dopamine release peak amplitude and (B) percent baseline stimulated dopamine in young (left; PD = 84 ± 7; GH n = 5; SI n = 5) and adult (right; PD = 181 ± 7; GH n = 4; SI n = 4) SI and GH rats. Quinpirole significantly reduced dopamine signals to the same extent in GH- and SI-reared rats for both young and adult cohorts.