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. Author manuscript; available in PMC: 2013 Aug 19.
Published in final edited form as: J Neuroimmune Pharmacol. 2011 Dec 10;7(2):388–400. doi: 10.1007/s11481-011-9325-0

Figure 2.

Figure 2

LM11A-31 supports survival of feline neurons in low density cultures. Feline neurons were cultured at a density of 23–40 cells/mm2 in the presence or absence of 10 nM LM11A-31. A. Three days after seeding, untreated neurons were present at an average (± sem) density of 13.7/mm2 (34.2% survival) whereas in the presence of LM11A-31 a significantly higher density of 22.9/mm2 (57.3% survival) was seen (p=0.0110 LM11A-31 vs. untreated, n=12 cultures each). B. A significant effect of LM11A-31 was also seen in the outgrowth of neurons after 14 days of continuous treatment. An average of 3.6% of the culture surface was occupied by MAP-2 immunoreactive cells and processes in the LM11A-31 cultures relative to 0.86% in the untreated cultures (p=0.039 LM11A-31 vs. untreated, n= 6 cultures each).