TABLE I.
Push beam 1 | Push beam 2 | Push beam 3 | |
---|---|---|---|
Focal location (z, mm) | 125 | 120 | 115 |
Lateral/axial (−6 db) beamwidth* on P− pressure profile (mm) | 3.5/38 | 3.2/36 | 3.0/35 |
Lateral/axial (−6 db) beamwidth* on P+ pressure profile | 2.3/34 | 2.1/32 | 2.0/28 |
P−/P+ Pressure** (MPa) | |||
Phantom | −5/14 | −5/15 | −5/16 |
Ex vivo tissue | −6/30 | −6/34 | −7/36 |
Pulse duration (μs) | |||
Phantom | 133 | 133 | 133 |
Ex vivo tissue | 200 | 200 | 200 |
ISPPA*** (kW/cm2) | |||
Phantom | 1.3 | 1.5 | 1.6 |
Ex vivo tissue | 2.3 | 2.5 | 2.8 |
Note that the beamwidth was narrower for shorter focal length (or smaller f-number).
The pressures at the treatment locations were expected to be lower than these measurements because of sound attenuation. Given a mean propagation distance of 3 cm and attenuation coefficients of 0.1 dB/cm/MHz in the agar-graphite phantoms [54], and 1 dB/cm/MHz in the kidneys [55], the P− pressures were estimated to be ~5 MPa both in the phantom and the ex vivo experiments.
ISPPA = spatial peak pulse average intensity.