Table 2. Summary of differentiated metabolites.
| # | parent ions | Retention time (min) | VIP | formula | metabolite ID | metabolic Pathway | HMDB ID | PubChem ID | KEGG ID | p value1 | trends2 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 307.18 | 12.67 | 15.42 | C6H14O10P2 | diphosphomevalonate | terpenoid backbone biosynthesis | HMDB01090 | 516 | C01143 | <0.05 | increase |
| 2 | 539.28 | 19.83 | 10.97 | C27H40O11 | tetrahydroaldosterone-3-glucuronide | pentose and glucuronate interconversions & Starch and sucrose metabolism | HMDB10357 | 167918 | C03033 | <0.05 | decrease |
| 3 | 331.19 | 21.46 | 9.57 | C21H32O3 | 21-hydroxypregnenolone | steroid hormone biosynthesis | HMDB04026 | 440705 | C05485 | <0.05 | increase |
| 4 | 308.16 | 12.67 | 9.25 | C11H19NO9 | N-acetylneuraminic acid | amino sugar and nucleotide sugar metabolism | HMDB00230 | 439197 | C00270 | <0.05 | increase |
| 5 | 526.45 | 24.84 | 9.14 | C16H25N4O10P2S | 3-carboxy-1-hydroxypropyl-ThPP | citrate cycle (TCA cycle) | HMDB06744 | 440649 | C05381 | <0.05 | decrease |
| 6 | 525.43 | 19.45 | 8.28 | C24H40N5O8 | desmosine | amino acids and amino acid conjugates metabolism | HMDB00572 | 25435 | - | <0.05 | increase |
| 7 | 495.26 | 26.45 | 7.67 | C27H44O8 | pregnanediol-3-glucuronide | pentose and glucuronate interconversions & starch and sucrose metabolism | HMDB10318 | 123796 | C03033 | <0.05 | decrease |
| 8 | 369.18 | 26.79 | 7.57 | C20H34O6 | 6-keto-prostaglandin F1a | arachidonic acid metabolism | HMDB02886 | 5280888 | C05961 | <0.05 | increase |
| 9 | 541.31 | 17.94 | 5.73 | C27H42O11 | cortolone-3-glucuronide | pentose and glucuronate interconversions & starch and sucrose metabolism | HMDB10320 | 125853 | C03033 | <0.05 | decrease |
1
It is considered as significant difference in this study when P value is less than 0.05
2
Urinary level in patients with UTI when comparing with controls.