Table 3.
Effect of various treatments on the plasma levels of antioxidant enzymes SOD and CAT in adjuvant-induced arthritis in rats.
| Treatment | SOD (U/ml) | CAT(U/ml) |
| IFA | 21.34±3.50* | 122.40±8.48 |
| CFA | 11.10±0.98 | 90.09±4.34 |
| HLE | ||
| 10 mg kg−1 | 28.40±1.18* | 77.42±2.71 |
| 30 mg kg−1 | 7.66±1.73 | 80.46±19.12 |
| 100 mg kg−1 | 11.73±1.34 | 86.29±22.38 |
| 300 mg kg−1 | 16.02±6.04 | 66.22±21.10 |
| Dexamethasone | ||
| 0.3 mg kg−1 | 9.54±0.80 | 84.79±18.69 |
| 1.0 mg kg−1 | 8.17±1.78 | 97.44±33.00 |
| 3.0 mg kg−1 | 8.75±1.18 | 96.47±9.57 |
| Methotrexate | ||
| 0.1 mg kg−1 | 8.61±0.30 | 108.61±8.59 |
| 0.3 mg kg−1 | 11.32±0.80 | 102.3±16.16 |
| 1.0 mg kg−1 | 7.28±0.88 | 51.54±13.01 |
Values are mean±SEM (n=3).
*
P<0.05 compared to CFA group (One-way ANOVA followed by Newman-Keuls post hoc test).
SOD: Superoxide dismutase; CAT: Catalase.