Table 5.
Individual patient responses to Jinfukang administration (N = 21)
Variable | Decrease (<67% of value for initial dose) |
No change (67–133% of value for initial dose) |
Increase (>133% of value for initial dose) |
---|---|---|---|
Concentration at 15 min | 3 (14) | 9 (43) | 9 (43) |
Concentration at 45 min | 4 (19) | 6 (29) | 11 (52) |
Area-under-the-curve at infinity |
2 (10) | 7 (33) | 12 (57) |
Area-under-the-curve at final time point |
3 (14) | 7 (33) | 11 (52) |
Clearance rate (L/h) | 5 (24) | 8 (38) | 8 (38) |
Volumes of distribution (Vd) by the steady- state method |
3 (14) | 4 (19) | 14 (67) |