(A) The normal morphology of neurons: The cell bodies were well stacked, the cellular membranes were smooth, and the neurites were thick (SEM ×3500). (B) The morphology of neurons under hypoxia: The cell bodies were smaller, the cellular membranes were crimpled, and the neurites were broken or had disappeared (SEM ×3500). (C). The morphology of neurons pretreated with Gin under hypoxia: The neurites were thinner and broken or had disappeared (SEM ×3500). (D) The normal morphology of neurons: Nuclear membranes were complete and smooth; chromatin was well distributed, and the structure of the endoplasmic reticulum was clear (TEM ×6000). (E) The morphology of neurons under hypoxia: The color of the cell nucleus was deepened, the nuclear membranes were not complete, the kytoplasm was condensed, and the rough endoplasmic reticulum was expanded (TEM ×6000). (F) The morphology of neurons pretreated with Gin under hypoxia: The nuclear membranes were complete, the kytoplasm was condensed slightly, and the rough endoplasmic reticulum was expanded slightly (TEM ×6000). (G) The morphology of neurons pretreated with GDNF under hypoxia: The nuclear membranes were complete; the kytoplasm was condensed slightly, and the rough endoplasmic reticulum was expanded slightly (TEM ×6000).