Table 3.
Mortality percentage and LD50 values in Opuntia ficus indica and Pistacia lentiscus -treated mice with oral or intraperineal single doses.
| Oral administration |
Opuntia ficus indica |
Dose (ml/kg body wt.) |
10 | 20 | 30 | 40 | 50 | 60 | 70 |
| Mortality (%) | 0 | 10 | 20 | 40 | 70 | 90 | 100 | ||
| LD50 : 43 ± 0,8 ; CI: [40.7– 45.4 ] ml/kg body wt. | |||||||||
|
Pistacia lentiscus |
Dose (ml/kg body wt.) |
10 | 20 | 30 | 40 | 50 | 60 | ||
| Mortality (%) | 0 | 10 | 30 | 60 | 80 | 100 | |||
| LD50 : 37 ± 1 ; CI: [34.4 – 39.8 ] ml/kg body wt. | |||||||||
| Intraperitoneal administration |
Opuntia ficus indica |
Dose (ml/kg body wt.) |
0.5 | 1 | 2 | 3 | 4 | 5 | 6 |
| Mortality (%) | 0 | 10 | 40 | 60 | 80 | 90 | 100 | ||
| LD50 : 2.72 ± 0,1 ; CI: [2.52-2.92] ml/kg body wt. | |||||||||
|
Pistacia lentiscus |
Dose (ml/kg body wt.) | 0.5 | 1 | 2 | 3 | 4 | 5 | ||
| Mortality (%) | 0 | 10 | 50 | 60 | 80 | 100 | |||
| LD50 : 2.52 ± 0,2 ; CI: [2.22 – 2.81 ] ml/kg body wt. | |||||||||
LD50 - lethal dose 50; CI - confidence intervals; values are expressed as mean ± SD.
LD50 was determined using the method of Kabba and BERHENS (Adjoungoua et al, 2008).