Table 3. Brain Activation to Stroop Interference from Color, Alcohol, Negative, and Positive-Emotion words in ALC and CTL.
MNI coordinates |
||||||
---|---|---|---|---|---|---|
Region | BA | P FDR extent | T | x | y | z |
(A) Group-by-Stroop interactiona | ||||||
Alcohol Stroop>color Stroop | ALC>CTL | |||||
L Parahippocampal gyrus | 19 | 0.0001 | 3.75 | −30 | −44 | −10 |
L Midbrain—substantia nigra | 4 | −10 | −24 | −12 | ||
R Midbrain—red nucleus | 2 | −28 | −12 | |||
Positive-emotion Stroop>color Stroop | ALC<CTL | |||||
L DLPFC—middle frontal gyrus | 9 | 0.009 | 3.97 | −44 | 10 | 40 |
6 | 3.93 | −40 | 6 | 50 | ||
9 | 3.69 | −34 | 22 | 26 | ||
(B) Group effectsb | ||||||
Color Stroop | CTL=ALC | |||||
L DLPFC—middle frontal gyrus | 46 | 0.094c | 3.69 | −44 | 16 | 22 |
L—middle frontal gyrus | 9 | −48 | 20 | 38 | ||
L—inferior frontal gyrus | 9 | −42 | 6 | 24 | ||
Alcohol Stroop | ALC>CTL | |||||
L+R Midbrain | 0.005 | 3.75 | 0 | −30 | −10 | |
L Parahippocampal gyrus | 19 | −30 | −44 | −8 | ||
R Midbrain—red nucleus | 6 | −20 | −10 | |||
Negative-emotion Stroop | No suprathreshold voxels | |||||
Positive-emotion Stroop | ALC<CTL | |||||
L DLPFC—middle frontal gyrus | 9 | 0.096c | 3.66 | −44 | 10 | 40 |
6 | 3.37 | −40 | 6 | 50 | ||
9 | 3.29 | −34 | 24 | 24 |
Group-by-Stroop interaction; PFDR-corrected<0.05 for extent for the whole-brain volume and Puncorr<0.001 for peak.
Group effects; PFDR-corrected<0.05 for combined peak and extent threshold (Poline et al, 1997).
Statistical trend, PFDR-corrected>0.05 and <0.01.