Figure 3.
Interaction between the BLA and vHipp inputs to the mPFC in MAM- and saline-treated rats. (a) Effect of subthreshold BLA stimulation on vHipp-evoked spike probability in mPFC in MAM- and saline-treated rats. BLA input increased vHipp-evoked spike probability at long ISIs to a similar extent in both saline and MAM rats. In contrast, subthreshold BLA stimulation did not have any inhibitory effect on vHipp-evoked spike probability at short ISIs in MAM rats compared with saline rats. (**p<0.001, two-way ANOVA; Tukey's post hoc test). (b) Effect of subthreshold vHipp stimulation on BLA-evoked spike probability in mPFC in MAM- and saline-treated rats. Spike probability was normalized to BLA threshold in control group. In MAM-treated rats, vHipp stimulation showed a selective decrease in evoked spike probability at short ISIs compared with controls (*p<0.05).