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No differences between wild-type (WT) and P2 × 4R knockout (KO) mice in spontaneous locomotor activity measured in the open field arena. (a) Total distance and (b) % locomotor activity in the center was similar between WT, heterozygous (HZ), and P2 × 4R KO mice. (c) Time in the center was significantly reduced in HZ mice. Data are shown as mean±SEM for 7–11 mice per genotype. *P<0.05 compared with WT mice.
