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. 2013 Jul 29;110(33):E3100–E3108. doi: 10.1073/pnas.1307096110

Fig. 3.

Fig. 3.

Elevated blood leukocyte counts are prevented by SkQR1 in pyelonephritic rats. Higher leukocyte (A), especially neutrophil (B) and monocyte (C), concentration in blood after induction of pyelonephritis with unchanged lymphocyte concentration (D). Production of proinflammatory TNFα (E) by leukocytes subsequent to pyelonephritis was elevated. Augmentation of neutrophils was accompanied by ROS burst in these cells (F). All of these inflammatory changes were prevented by SkQR1 treatment. *P < 0.01, **P < 0.05.