Table 1.
ERG construct ITC results
| Construct | n | KD | Fold inhibition |
| 1–462 | 1.05 (±0.04) | 121 (±5) | 3.3 |
| 210–462 | 1.10 (±0.02) | 104 (±6) | 2.8 |
| 272–412 | 0.94 (±0.03) | 101 (±8) | 2.7 |
| 272–388 (ERGi) | 0.98 (±0.03) | 176 (±10) | 4.8 |
| 289–412 | 0.98 (±0.06) | 51 (±10) | 1.4 |
| 272–378 | 0.99 (±0.03) | 33 (±3) | 0.9 |
| 289–388 | 0.99 (±0.02) | 41 (±4) | 1.1 |
| 289–378 (ERGu) | 1.04 (±0.02) | 37 (±3) | 1.0 |
| ERGu Y354F | 1.00 (±0.03) | 106 (±6) | 2.9 |
| ERGi Y354F | 1.01 (±0.04) | 200 (±13) | 5.4 |
| ERGi S283A | 1.01 (±0.04) | 97 (±11) | 2.6 |
Stoichiometry, dissociation constant, and relative inhibition of ERG truncation constructs and point mutants. KD is given in nanomolar. Numbers in parentheses are ±SE.