Table 1.

In vitro inhibition of Leishmania promastigotes by AGs along with their MIC values in E. coli

Aminoglycoside	LC50, μM		MIC, μM
	L. major	L. donovani	E. coli
Paromomycin	31.4 ± 5.7, n = 5*	48.1 ± 5.8, n = 6*	22†
Neomycin	>1,000	>2,000	24†
G418	1.95 ± 0.05, n = 2*	5.8 ± 0.9, n = 4*	9†
Gentamicin	273.1	>2,000	6†
Apramycin	>1,000	>2,000	2–3‡

MIC, minimum inhibitory concentration.

^*Each value represents the mean ± SE of n repeats. Growth inhibition curves are presented in Fig. S6.

^†MIC values in E. coli were previously reported (31–33).

^‡MIC values were calculated from Matt et al. (34).