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. 2013 Jul 31;110(33):13534–13539. doi: 10.1073/pnas.1312911110

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Fig. 6. — Increased expression of IL-15 and IL-15Rα in patients with T1D. (A) Immunohistochemistry staining of IL-15 in pancreatic tissues from T1D, autoantibody positive (Aab), and normal donors (Ctrl). (B) IL-15 mRNA levels in microdissected islets analyzed by Nanostring. The counts were normalized to three housekeeping genes. T1D vs. ctrl: P < 0.01. (C) IL-15Rα mRNA levels in microdissected islets analyzed by Nanostring. The counts were normalized to three housekeeping genes. T1D vs. ctrl: P = 0.07. (D) sIL-15Rα levels in the serum from 29 controls and 20 T1D patients (P < 0.001).