Figure 2.

Biological and phenotypic changes in the aging and diabetic heart (A). Fasting blood glucose levels (Accu-chek system, Roche) and (B) HbA1c (A1C now+ test kit. Bayer, UK) were taken at least 48 h prior to excision of the heart. Data are shown as mean ± SEM, n ≥ 10. **P < 0.005, ***P < 0.001 vs. 3-month GK measurements. One-way ANOVA and Tukey's post hoc analysis were used for statistical analysis between all groups. (C) Heart/body weight ratio (HW/BW%) was calculated following the experimental investigations. Data were analysed using Pearson's regression analysis.