Figure 6.

Cardiac function assessment in the aging, non-diabetic heart. The old, non-diabetic Wistar rat hearts exhibit no significant differences in cardiac function compared with young, non-diabetic hearts in response to ischaemia/reperfusion. (A) HR, (B) LVDP, and (C) RPP were calculated as HR × LVDP as a measure of cardiac workload. (D) Recovery of LVDP (% resting LVDP/end of reperfusion LVDP). Data are shown as mean ± SEM, n ≥ 6. Student's t-test was used for statistical analysis between 3- and 18-month groups.