Table 5. Association of the BTNL2 (rs3817963) single nucleotide polymorphism and ancestral informative marker (rs30533) with self-reported measures of sarcoidosis severity.
| Cases (n) | Per allele OR (95 % CI) | ||
|---|---|---|---|
|
| |||
| BTNL2 (rs3817963)a | Ancestral Informative Marker-Ancestry association test (rs30533) | ||
| ≥4 symptoms at diagnosisb | 133 | 1.31 (0.91–1.88) | 0.70 (0.46–1.07) |
| Fair or poor healthc | 80 | 1.36 (0.86–2.17) | 0.80 (0.46–1.39) |
| Little or no ability to carry out everyday physical activitiesc | 35 | 1.31 (0.66–2.58) | 1.03 (0.45–2.34) |
| Severe or very severe fatiguec | 44 | 1.17 (0.65–2.10) | 1.26 (0.57–2.79) |
| ≥5 on the pain scalec | 107 | 1.45 (0.96–2.20) | 0.85 (0.52–1.39) |
a
Perfect proxy (r2 = 1.0) of rs9268480 in Hapmap YRI
b
Data obtained from BWHS Sarcoidosis Supplemental Survey. (Cozier et al. 2011)
c
Data obtained from BWHS 2011 questionnaire