Table 5.
Gene | SNPs | Genotype | No. of patients (events) | HRa (95% CI) | P value (global testing) |
---|---|---|---|---|---|
NFKB1 | 3774932 | AA + AG | 232 (58) | 1(reference) | |
GG | 120 (38) | 2.52 (0.91,2.89) | 0.03 | ||
TNF | 1799964 | CC + CT | 232 (58) | 1 | |
TT | 9 (4) | 2.52 (0.91,6.95) | 0.07 | ||
IL4R | 3024543 | GG | 400 (86) | 1 | |
AG + AA | 323 (94) | 1.57 (0.93,2.64) | 0.09 |
Abbreviations: HR: hazard ratio; CI: confidence interval