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IC50 of inhibition of breast cancer cells growth by compounds 44, 30 and nimesulide
| Breast cancer cell lines | Comp 44 | Comp 30 | Nimesulide |
|---|---|---|---|
| SK-BR-3 | 6.2 ± 1.8 μM | 20.1 ± 5.5 μM | 111.8 ± 32.3 μM |
| MDA-MB-231 | >50 μM | >50 μM | 123.4 ± 10.8 μM |
| MCF-7 | >50 μM | >50 μM | 120.4 ± 8.6 μM |
| BT-474 | 13.5 ± 2.6 μM | 44.7 ± 16.3 μM | 165.9 ± 22.5 μM |
Cells were treated with indicated compounds at various concentrations for 48h and cell viability was measured by MTT assay as described in the experimental section, n = 6.
