Table 4.
Area of Activation | Brodmann area | Side | Cluster size | Talairach coordinates |
F (2, 50) |
Between-group differences | ||
---|---|---|---|---|---|---|---|---|
x | y | z | ||||||
Anterior cingulate gyrus | 24 | L | 149 | − 4 | 11 | 32 | 8.42 | Angry: BD<SMD⁎⁎, BD<HV⁎ |
Anterior cingulate gyrus | 24 | R | 27 | 5 | 11 | 32 | 5.39 | Angry: BD<SMD⁎⁎ |
Posterior cingulate gyrus | 31 | L | 65 | − 4 | − 28 | 35 | 5.68 |
Angry: BD<SMD⁎, BD<HV⁎⁎ Fearful: SMD<BD⁎, SMD<HV⁎ |
Posterior cingulate gyrus | 31 | R | 30 | 2 | − 34 | 41 | 5.17 |
Angry: BD<HV⁎⁎, SMD<HV⁎ Fearful: BD<HV† SMD<HV⁎⁎ |
Posterior insula | 13 | L | 45 | − 37 | − 22 | 14 | 5.19 |
Angry: BD<SMD⁎, BD<HV⁎ Fearful: SMD<BD⁎, SMD<HV⁎ |
Posterior insula | 13 | R | 92 | 35 | − 16 | 11 | 5.28 | Angry: BD<SMD⁎⁎, BD<HV⁎⁎ |
Inferior parietal lobe | 40 | L | 69 | − 31 | − 52 | 35 | 6.32 |
Angry: BD<SMD⁎, BD<HV⁎⁎ Fearful: SMD<BD†, SMD<HV⁎⁎ |
p < .05 (corrected).
BD = bipolar disorder, SMD = severe mood dysregulation, HV = healthy volunteer.
x,y, and z coordinates refer to the voxel with maximum signal intensity.
Note: The post-hoc analyses of angry, fearful, neutral expressions were conducted in regions identified by the primary Group × Emotion ANOVA analysis.
p < .10.
p < .05.
p < .01.