Table 1.
Comparison of neurochemical metabolites in depression group and control group in prefrontal cortex
| Variables | Depression group (n = 39) Mean ± SD | Control group (n = 16) Mean ± SD | z* | P** |
|---|---|---|---|---|
| Age | 35.82 ± 12.93 | 31.31 ± 5.65 | 0.909 | 0.363 |
| Education years | 9.51 ± 4.65 | 9.43 ± 4.70 | 0.363 | 0.985 |
| NAA | 61.71 ± 17.08 | 66.37 ± 9.87 | 1.548 | 0.122 |
| Cho | 35.68 ± 7.41 | 35.31 ± 6.34 | 0.052 | 0.958 |
| Cr | 37.98 ± 9.11 | 38.75 ± 6.86 | 0.306 | 0.759 |
| NAA/Cr | 1.59 ± 0.33 | 1.73 ± 0.21 | 1.772 | 0.076 |
| Cho/Cr | 0.99 ± 0.25 | 0.94 ± 0.13 | 0.291 | 0.771 |
Notes:
*
Mann–Whitney U test;
**
P < 0.05 shows significance.
Abbreviations: NAA, N-acetyl aspartate; Cho, choline; Cr, creatine; SD standard deviation; n, number.