Table 1. Characteristics of all Eligible Orthotopic Liver Transplant Recipients and Donors in the Study (N=307).
Variable | |
---|---|
Age (median, IQR) | |
Recipient | 51 (41-56) |
Donor | 46 (34-55) |
Gender donor/recipient, N (%) | |
Male/male | 105 (34.2) |
Male/female | 52 (16.9) |
Female/male | 85 (27.7) |
Female/female | 65 (21.2) |
Primary liver disease, N (%) | |
Viral | 59 (19.2) |
Alcoholic | 46 (15.0) |
Cholestatic | 79 (25.7) |
Other disease§ | 123 (40.1) |
Child-Pugh class, N (%) | |
A | 67 (21.8) |
B | 138 (45.0) |
C | 102 (33.2) |
Lab MELD score (median, IQR) | 15 (11-21) |
Donor-type, N (%) | |
Donation after cardiac death | 24 (7.8) |
Donation after brain death | 283 (92.2) |
Maintenance immunosuppression, N (%) | |
Prednisone / CNI / basiliximab (+ MMF) | 206 (67.1) |
Prednisone / CNI (+ azathioprine) | 101 (32.9) |
Acute cellular rejection, N (%) | |
Yes | 107 (34.9) |
No | 200 (65.1) |
Bacterial infection, N (%) | 94 (30.6) |
LCBI | 52 (55.3) |
PNEU | 10 (10.6) |
IAB | 32 (34.0) |
IQR denotes interquartile range; MELD, Model for End-Stage Liver Disease; CNI, calcineurin inhibitors; MMF, mycophenolate mofetil; LCBI, laboratory-confirmed bloodstream infection; PNEU, pneumonia; IAB, intra-abdominal infection.
§ Other diseases included predominately autoimmune hepatitis, cryptogenic cirrhosis and metabolic disorders.