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. 2013 Sep;94(3):399–407. doi: 10.1189/jlb.0512249

Figure 1. HIV increases Etd uptake in a biphasic manner in human primary PBMCs and CD4+ T lymphocytes.

Figure 1.

(A–D) Time course of Etd uptake rate obtained from PBMCs or CD4+ T lymphocytes under control conditions (squares) or after infection with HIV (circles), 0–120 h. PBMCs infected with HIVADA (A) and CD4+ T lymphocytes infected with HIVADA (B), HIVBal (C), or HIVLAI (D). (E and F) Representative time-lapse measurements of Etd uptake in CD4+ T lymphocytes under control conditions (squares) or after 5 min (E) or 72 h (F) of exposure to HIVADA (circles). No differences were observed between R5 and X4 isolates. *P < 0.005; **P < 0.002 ; ***P = 0.0001 denote significance as compared with control conditions. Each value corresponds to the mean ± sd of the Etd intracellular intensity, present in at least 20 cells/time-point (n=4).