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. 2013 Aug 19;8(8):e72141. doi: 10.1371/journal.pone.0072141

Table 1. Demographic characteristics of whole cohort.

Demographic characteristics Whole cohort
Number of patients n (%) 70 (100)
Age (Years) Mean (median)range 6.5 (5.0) 0.1–19.9
Body weight (Kg) Mean (median)range 27.0 (20.8) 4.3–95.6
Gender n (%) Male 41(58.6)
Females 29 (41.4)
Diagnosis n (%) AML 26 (37.1)
MDS 12 (17.1)
Immunodeficiency 11 (15.7)
ALL 9 (12.9)
Metabolic disease 5 (7.1)
Hemophagocytic syndrome 5 (7.1)
Hemoglobinopathies 1 (1.4)
Neuroblastoma 1 (1.4)
Conditioning regimen n (%) Bu+Cy 53 (75.7)
Bu+Cy+Mel 3 (4.3)
Bu+Cy+VP16 7 (10)
Bu+Flu 4 (5.7)
Bu+Mel 3 (4.3)
Disease status in malignancies n (%) First acute phase of the disease 1(2.7)
First CR 18(50.0)
second CR 12(33.3)
third or more CR 2(5.5)
First Relapse 3(8.3)
HLA Matching n (%) 3/6 2 (2.9)
4/6 20 (28.6)
5/6 28 (40)
6/6 16 (22.9)
7/8 1 (1.4)
8/8 2 (2.9)
7/10 1 (1.4)
HLA match compatibility n (%) MRD 2(2.8)
MUD 16 (22.9 )
MMU 52 (74.3)
Days after transplant Mean (median) 1064.4 (815.0)
Nucleated cells injected (108/kg) Mean (median)range 2.1 (1.4) 0.16–18.0
CD34+ cells injected (108/kg) n = 64 Mean (median)range 0.02 (0.004) 0.0005–0.14

Abbreviations: ALL: acute lymphoblastic leukemia; AML: acute myeloid leukemia; ATG: anti-thymocyte globulin; Bu: busulfan; Cy: cyclophosphamide; CR: Complete remission; Flu: fludarabine; MDS: myelodisplastic syndrome; Mel: melphalan; MMU: mismatch unrelated; MRD: matched related donor; MTX: methotrexate; MUD: matched unrelated donor; VP16: etoposide.