Figure 6. Edge weights over the disease severity score for two representative edges of the identified sub-networks in patients with svMCI and SVaD: the edge between the medial surface of left superior frontal gyrus (SFGmed.L) and the left median cingulate and paracingulate gyri (DCG.L) in patients with svMCI (A) and SVaD (B); and the edge between the orbital part of left inferior frontal gyrus (ORBinf.L) and left insula (INS.L) in patients with svMCI (C) and SVaD (D).
A circle represents each subject, dotted horizontal lines represent zero edge weights, and solid lines represent linearly regressed lines. The noted correlation coefficient and p-values were calculated using Pearson correlation without any covariates. The former edge (A&B) belonged to the identified sub-network in patients with svMCI, and thus had a strong correlation coefficient in patients with svMCI; however, in patients with SVaD, about half of the subjects had zero or very low weights (20 over 45), resulting in a low correlation coefficient. The latter edge (C&D) belonged to the identified sub-network in patients with SVaD, and thus had a strong correlation coefficient in patients with SVaD; however, in patients with svMCI it is not the case.