Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Aug 19;8(8):e71782. doi: 10.1371/journal.pone.0071782

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Jia et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

The vertical axis represents the gene expression, which is normalized to FPKM. The red arrows indicate the variation trend of FPKM for abnormal up-regulated genes in RPS19 MO, and the green arrows indicate the down-regulated genes in RPS19 MO. Solid arrows indicate the variation trend of FPKM of genes in RPS19 MO, and dashed arrows indicate the variation trend of FPKM of genes in RPS19+p53 MO. Up−/down-regulated genes are screened with the criterion of a fold-change of >2.0 and a p-value of <0.05. (A) Up−/down-regulated genes in RPS19 MO compared with the control and down−/up-regulated genes in RPS19+p53 MO compared with RPS19 MO; we considered genes that satisfied the above criteria to be genes that are p53 dependent. (B) Up−/down-regulated genes in RPS19 MO compared with the control and up−/down-regulated genes in RPS19+p53 MO compared with the control; we considered genes that satisfied the above criteria to be genes that are independent of p53.