Skip to main content
. 2013 Aug 19;8(8):e71399. doi: 10.1371/journal.pone.0071399

Figure 2. Combined effects of increasing numbers of isolated postprandial hyperglycaemia-associated risk alleles from TCF7L2, CDKAL1, KCNQ1, PRC1, TP53INP1 and GCKR.

Figure 2

A: The isolated postprandial hyperglycaemia-associated risk allele distribution in controls, participants with isolated fasting hyperglycaemia and isolated postprandial hyperglycaemia. Each additional risk allele increased the risk of isolated postprandial hyperglycaemia by 1.19-fold (p<0.0001) (B) but not the risk of isolated fasting hyperglycaemia (C). OR and 95% CI were plotted on the y-axis for the corresponding number of risk alleles on the x-axis (black circles  =  risk of isolated fasting hyperglycaemia; white circles  =  risk of isolated postprandial hyperglycaemia). B: Participants harboring eight or more risk alleles had a 2.31-fold increased risk for isolated postprandial hyperglycaemia (p<0.0001) compared with the reference group. C: However, risk for isolated fasting hyperglycaemia was not increased as risk allele number increasing. IFH, isolated fasting hyperglycemia; IPH, isolated postprandial hyperglycemia.