Table 1. Clinical characteristics of study population.
Isolated fasting | Isolated postprandial | All newly diagnosed | ||
control | hyperglycaemia | hyperglycaemia | type 2 diabetes | |
Samples ( n ) | 4,254 | 341 | 865 | 2,409 |
Male/Female ( n ) | 1,382/2,872 | 175/166 | 382/483 | 1,062/1,347 |
Age (years) | 50.69±8.38 | 51.19±12.58 | 56.17±11.52 | 55.20±11.60 |
BMI (kg/m2) | 23.07 (21.28,24.77) | 25.26 (23.03,28.56) | 25.77 (23.52,28.13) | 25.85 (23.62,28.33) |
Fasting plasma glucose (mmol/l) | 5.02 (4.68,5.40) | 7.53 (7.20,8.26) | 6.00 (5.45,6.50) | 7.49 (6.41,9.16) |
30min plasma glucose (mmol/l) | 8.10 (7.00,9.20) | 11.10 (9.20,12.98) | 11.30 (9.64,12.79) | 12.27 (10.32,14.55) |
2h plasma glucose (mmol/l) | 5.76 (4.90,6.60) | 8.41 (6.71,9.70) | 12.61 (11.76,14.18) | 13.70 (11.72,17.19) |
Fasting serum insulin (mU/l) | 6.31 (4.90,8.45) | 9.10 (6.14,12.30) | 8.16 (5.93,11.66) | 8.80 (6.12,12.62) |
30min serum insulin (mU/l) | 33.09 (20.92,52.64) | 28.18 (17.05,47.99) | 25.84 (15.11,43.80) | 20.67 (11.87,36.86) |
2h serum insulin (mU/l) | 22.37 (13.94,34.96) | 29.26 (17.97,49.56) | 50.96 (26.56,90.70) | 33.44 (19.07,61.04) |
HOMA-IR | 1.40 (1.06,1.90) | 3.22 (2.12,4.47) | 2.15 (1.49,3.10) | 3.07 (1.98,4.61) |
HOMA-B (%) | 85.55 (61.09,125.08) | 42.47 (29.30, 61.20) | 71.58 (47.89, 102.95) | 45.27 (27.62,73.88) |
ISIm | 8.38 (6.19, 11.34) | 4.35 (3.08, 6.32) | 4.66 (2.97, 6.82) | 4.13 (2.78, 6.04) |
Insulinogenic index (ΔI30/ΔG30) | 9.40 (5.03,17.31) | 4.74 (2.10,11.68) | 3.36 (1.78,6.78) | 2.68 (1.29,5.98) |
Prevalence of cardiovascular diseases (%, ntotal / naffected ) | 3.25%, 3,422/115 | 6.72%, 250/18 | 11.72%, 625/83 | 11.18%, 1,967/220 |
Data are shown as mean ± SD for normally distributed values, median (interquartile range) for non-normally distributed values, or n (%).