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. 2013 Aug 19;8(8):e71140. doi: 10.1371/journal.pone.0071140

Table 2. Main results for meta-analysis between SOX2 and clinicopathological Parameters.

clinical parameters No. of studies overall OR (95%CI) Heterogeneity test (Q, I2, P)
Sex (male vs. female) (1),(4),(5),(6),(7) 1.49 (0.69–3.23) 10.6, 62.3%, 0.312 (random-effect)
Age (>60 vs. < = 60) (1),(5),(6),(7) 1.30 (0.84–2.01) 3.88, 22.7%, 0.236 (fixed-effect)
Smoking status (yes vs. no) (1),(4),(5),(7) 2.40 (0.95–6.05) 6.79, 55.8%, 0.065 (random-effect)
Histology (SCCvs. ADC) (2),(3),(4),(5),(6),(7) 5.26 (1.08–25.6) 78.2, 93.6%, 0.040 (random-effect)
Differentiation (poor vs. well) (5),(6),(7) 1.97 (0.96–4.05) 0.49, 0.0%, 0.066 (fixed-effect)
Lyphmnodemetastsis (N1 vs. N0) (4),(5),(7) 1.30 (0.85–1.97) 1.48, 0.0%, 0.226 (fixed-effect)
Stage (III/IV vs. I/II) (4),(6),(7) 0.89 (0.55–1.44) 2.08, 3.9%, 0.621 (fixed-effect)

Abbreviations: SCC, squamous cell carcinomas; ADC, adenocarcinomas; OR, odds ratios.