Figure 5. The expression of CD247 by airway CD8 cells.
Bronchoalveolar lavage (BAL) was obtained from chronic obstructive pulmonary disease (COPD, n = 7), smokers with normal lung function (S, n = 4) and healthy non-smokers (HNS, n = 8). Cells were labelled with anti-CD8 (green) and anti-CD247 (red). Nuclei were counterstained with 4′,6-diamidino-2-phenylindole (DAPI, blue). Top panel: Representative images of COPD BAL cells. Merged image displays a CD8+CD247+ cell (yellow, arrow), a CD8+CD247- cell (green, arrow head) and a CD8-CD247+ (red). Lower panel: Percentage of BAL CD8 cells positive for CD247 in COPD, S and HNS. Statistical significance indicated by *p<0.05. Data was analysed by Kruskall-Wallis test followed by Dunn’s multiple comparisons test if p<0.05.