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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: J Immunol. 2013 Jun 14;191(2):614–622. doi: 10.4049/jimmunol.1203137

Figure 3. Ex vivo MOG35-55-specific T cell cytokine profiles and serum MOG35-55 specific IgG antibody response in immunized WT and H1-4RKO mice.

Figure 3

(A) MOG35–55-specific T-cell proliferative responses were evaluated by 3H-thymidine incorporation. Mean counts per minute ± standard deviation were calculated from triplicate wells of n = 10 per strain. (B) Serum MOG35–55-specific IgG Ab was measured by ELISA. The significance of differences in proliferation and antibody production were determined by two-way ANOVA followed by Bonferroni post-hoc multiple comparison test. (C) IFN-γ and (D) IL-17 production by MOG35–55 stimulated DLNs and splenocytes from WT and H1-4RKO mice were evaluated by ELISA and shown as mean ± SEM of n = 10 per strain. Significance of differences observed in cytokine production was determined by Mann Whitney test (**, p<0.01).