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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: J Immunol. 2013 Jun 14;191(2):614–622. doi: 10.4049/jimmunol.1203137

Table II.

Clinical disease traits following immunization of C57BL/6J, H1-4RKO with 2× MOG35–55 + CFA.

Strain Incidencea CDS PS DA DO SI LD
B6 16/20 (80) 14.6 ± 2.9 1.7 ± 0.2 8.4 ± 1.3 19.5 ± 1.0 1.7 ± 0.2 0/16
H1-4RKO 6/29 (21) 5.0 ± 1.9 0.6 ± 0.2 2.2 ± 0.8 20.2 ± 0.6 2.2 ± 0.2 0/6
p-value <0.0001 0.0007 0.0007 0.0002
a

Animals were considered affected if clinical scores ±1 were apparent for 2 or more consecutive days (percent affected). Cumulative disease score (CDS), peak score (PS) days affected (DA), day of onset (DO), severity index (SI), and lethal disease (LD). Mean trait values ± SE are shown. Significance of differences in trait values between the strains was assessed using the Fisher’s exact test (incidence) and Mann-Whitney test (clinical disease parameters).