Figure 4. The population doubling time (PDT) of TSCs isolated from mouse tendons.
TSCs were seeded in a 6-well plate and cultured to determine PDT. Mouse treadmill running enhanced proliferation of TSCs from patellar tendons (A) and Achilles tendons (B), as indicated by decreased PDT compared to cage controls. In fact, ITR stimulated cell growth more quickly than MTR (A, B) (*p<0.05 with respect to cage control; #p<0.05 with respect to MTR).