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Results of preliminary trials.
| Parameters | P1 | P2 | P3 | P4 | P5 | P6 | P7 | P8 | P9 |
|---|---|---|---|---|---|---|---|---|---|
| Drug loading (%) | 91.77 ± 3.45 | 82.46 ± 3.72 | 89.74 ± 4.70 | 88.24 ± 2.87 | 84.40 ± 3.88 |
SPHC was not formed |
74.53 ± 2.42 | 70.93 ± 2.08 |
SPHC was not formed |
| Bioadhesion time (h) | 8 | 7 | 5 | 8 | 8 | 8 | 8 | ||
| CPR* (%) | 99.10 | 100.84 | 100.20 | 98.03 | 94.98 | 87.22 | 81.24 | ||
| t 100% † (h) | 2 | 3 | 2 | 5 | 8 | 8 | 8 |
*CPR: cumulative percentage drug release; † t 100%: time required for 100% drug release.
