Table 2.
TAVI | SAVR | ANOVA | |||
---|---|---|---|---|---|
Baseline | 6 months | Baseline | 6 months | p Value | |
Left ventricle | |||||
LVEDVI (ml/m2) | 94±18 | 90±20 | 92±19 | 74±12** | 0.04 |
LVESVI (ml/m2) | 46±18 | 41±17* | 44±22 | 32±6* | 0.19 |
LVSVI (ml/m2) | 48±10 | 50±10 | 49±8 | 42±7* | 0.14 |
LVEF (%) | 52±12 | 56±10* | 55±11 | 57±8 | 0.57 |
LVM (g) | 153±48 | 120±38*** | 143±57 | 114±42*** | 0.53 |
LVMI (g/m2) | 83±20 | 65±17** | 74±11 | 59±8** | 0.35 |
LVM/LVEDV (g/ml) | 0.88±0.2 | 0.73±0.2*** | 0.80±0.1 | 0.81±0.2 | 0.001 |
Right ventricle | |||||
RVEDVI (ml/m2) | 77±19 | 74±13 | 78±14 | 76±17 | 0.60 |
RVESVI (ml/m2) | 38±13 | 35±10* | 31±7 | 34±10 | 0.80 |
RVSVI (ml/m2) | 39±9 | 39±9 | 47±11 | 41±14 | 0.37 |
RVEF (%) | 51±9 | 53±10 | 60±8 | 54±11* | 0.63 |
RVMI (g/m2) | 19±4 | 16±3** | 18±4 | 17±4 | 0.17 |
Aortic valve | |||||
Mean PG (mm Hg) | 58 (43–73) | 21±8*** | 51 (37–66) | 35±13** | 0.017 |
AR fraction (%) | 16±11 | 8±6* | 18±7 | 10±11 | 0.46 |
Mitral valve | |||||
MR fraction (%) | 20±16 | 14±23 | 2±8 | 2±6 | 0.007 |
Late gadolinium enhancement | |||||
Focal myocardial fibrosis | |||||
Mass (g) | 14.1±8 | 8.6±5*** | 5.9±3 | 5.1±3 | 0.005 |
Percentage myocardium (%) | 10.9±6 | 8.5±5* | 4.2±2 | 4.1±2 | 0.02 |
Myocardial scar (infarction) | |||||
Mass (g) | 20.6±12 | 13.8±11* | 22.7 | 18.0 | 0.80 |
Percentage myocardium (%) | 15.6±10 | 11.2±9 | 10.0 | 10.0 | 0.12 |
Values are mean±SD or median (interquartile range).
ANOVA repeated measure overtime with procedure as covariate. Paired t test vs baseline: *p<0.05, **p<0.01, ***p<0.001.
AR, aortic regurgitation; EDVI, end diastolic volume indexed to body surface area; EF, ejection fraction; ESVI, end systolic volume indexed; LV, left ventricle; LVM, left ventricular mass; mean PG, peak pressure gradient; MR, mitral regurgitation; RV, right ventricle; SVI, stroke volume indexed; TAVI, transcatheter aortic valve implantation.