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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Acta Astronaut. 2012 Aug 29;92(1):73–78. doi: 10.1016/j.actaastro.2012.08.007

Fig 2. Periosteal and endosteal bone formation in cortical bone is impaired in Igf-1r−/− mice.

Fig 2

(A) μCT analysis revealed that total cross-sectional area (Tt.Ar) of cortical bone was decreased in Igf-1r−/− male mice. n = 10 in the two groups. (B) Bone histomorphometry showed that bone formation rate (BFR/BS) was decreased in both periosteal and endosteal surfaces of cortical bone in Igf-1r−/− mice. n = 6 in Igf-1r+/+ mice; n = 7 in Igf-1r−/− mice. Data are percent of the results of Igf-1r+/+ mice and shown as mean ± SE. #p < 0.01.