Table 3.
Genotype and Allele Frequencies of rs3753841 Among Different Cases and Control Groups
|
rs3753841
(COL11A1) |
Genotype |
P
Value |
Allele |
P
Value |
OR (95% CI) |
|||||
|
Group |
N |
GG |
GA |
AA |
G |
A |
||||
| PACS | Cases | 164 | 40 (24.4%) | 74 (45.1%) | 50 (30.5%) | 0.459 | 154 (47%) | 174 (53%) | 0.213 | 1.11 (0.85–1.46) |
| Control | 360 | 71 (19.7%) | 177 (49.2%) | 112 (31.1%) | 319 (44.3%) | 401 (55.7%) | ||||
| PAC/PACG | Cases | 176 | 41 (23.2%) | 87 (49.5%) | 48 (27.3%) | 0.520 | 169 (48%) | 183 (52%) | 0.127 | 1.16 (0.89–1.51) |
| Control | 360 | 71 (19.7%) | 177 (49.2%) | 112 (31.1%) | 319 (44.3%) | 401 (55.7%) | ||||
| Any-angle closure group | Cases | 340 | 81 (23.8%) | 161 (47.4%) | 98 (28.8%) | 0.411 | 323 (47.5%) | 357 (52.5%) | 0.116 | 1.14 (0.92–1.41) |
| Control | 360 | 71 (19.7%) | 177 (49.2%) | 112 (31.1%) | 319 (44.3%) | 401 (55.7%) | ||||
P
values ≤0.05 were considered nominally significant, and P values <0.0167 were considered experiment-wise significant.