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Effect of heat stress over time on changes in body temperature (A) and skin tail temperature (B) and body temperature threshold for tail skin vasodilation (C) after bilateral PVN injection of CSF, lidocaine or L-NMMA. Values expressed as mean ± SEM. n = 6/group. Significantly different from basal value until the end of heat stress: + CSF; ϕ lidocaine; # L-NMMA. Significant difference between groups: π CSF X L-NMMA; $ L-NMMA X lidocaine, p<0.05.
