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. Author manuscript; available in PMC: 2013 Aug 20.
Published in final edited form as: Glia. 2011 Feb 3;59(4):641–654. doi: 10.1002/glia.21134

Fig. 11.

Fig. 11

Inflammatory cytokines increase reactive astrogliosis in Foxo3a null mouse. A, at 7 days after TNF-α and IL-1β (5 ng and 1 ng) intracranial injection, reactive astrogliosis in Foxo3a null mouse was detected by GFAP immunostaining (10× and 40×), wild type mice from the same litter were used as control. GFAP positive cell was quantified in total cells per area (B), and GFAP expression were also quantified by determining the GFAP-intensity (C). Total 30 pictures from 4 mice were calculated. **, p < 0.005 in comparison to control. ***, p < 0.001 in comparison to control.