. Author manuscript; available in PMC: 2013 Dec 1.

Published in final edited form as: J Med Virol. 2012 Dec;84(12):1901–1906. doi: 10.1002/jmv.23419

TABLE I.

Clinical Characteristics of Chronic HBV-Infection Patients With (Group I) and Without (Group II) MHR Mutations

	With MHR mutations (Group I, n = 75)	Without MHR mutations (Group II, n = 86)	P
Age (years)^a	49.13 ± 10.24	47.98 ± 12.55	0.526
Gender (M/F)^b	59/16	67/19	0.907
White blood cell count (×10⁹/L)^a	4.58 ± 1.99	5.39 ± 2.51	0.025^*
Platelet count (×10⁹/L)^a	125.87 ± 65.49	138.94 ± 64.82	0.206
Albumin (g/L)^a	41.08 ± 7.62	41.20 ± 5.88	0.907
Bilirubin (mmol/L)^a	21.9 (5.8–627.4)	16.9 (4.1–364.1)	0.048^*
ALT (IU/L)^a	47.0 (8.8–1001.6)	47.3 (3.2–1109.5)	0.740
Cirrhosis by ultrasound (%)^b	16 (21.3)	7 (8.1)	0.010^*
HBV DNA (log IU/ml)^a	4.13	4.36	0.584
HBsAg (COI)^a	4907.3 ± 1904.4	5517.9 ± 2144.4	0.255
HBsAb ( +/− )^a	17/58	0/86	0.000^*

MHR, major hydrophilic region; M, male; F, female; ALT, alanine aminotransferase.

Statistical significance was calculated using two independent samples t-test.

Gender and cirrhosis by ultrasound were calculated using Chi-square tests.

P < 0.05.