Table 3. Regression analysis of the effect of explanatory variables on the risk of transmission (early-onset).
Variables | Maternal Infection/Neonatal Infection (n = 16) | Maternal Colonization/Neonatal Infection (n = 14) | Maternal Colonization/Neonatal Colonization (n = 24) | Maternal Risk Factors/Neonatal Infection (n = 9) | ||||||||||||||||
n | βa | exp(β) | 95% CI | p-Value | n | β | exp(β) | 95% CI | p-Value | n | β | exp(β) | 95% CI | p-Value | n | β | exp(β) | 95% CI | p-Value | |
NMR | ||||||||||||||||||||
Very low mortality <5 per 1,000 live births | 14 | ref | 9 | ref | 18 | ref | 7 | ref | ||||||||||||
Low mortality 5–14 | 1 | 0.96 | 2.61 | 0.34–20.12 | 0.33 | 1 | −1.27 | 0.28 | 0.01–7.68 | 0.41 | 4 | 0.81 | 2.24 | 0.22–22.43 | 0.47 | 0 | — | |||
High mortality 15–27 | 0 | — | 1 | −0.50 | 0.61 | 0.01–58.87 | 0.81 | 1 | 4.93 | 139.06 | 2.08–9,312.79 | 0.02 | 0 | — | ||||||
Very high mortality >27 | 1 | −0.06 | 0.94 | 0.11–7.75 | 0.95 | 3 | 0.47 | 1.61 | 0.10–25.58 | 0.71 | 1 | −1.61 | 0.20 | 0.01–7.79 | 0.37 | 2 | −0.85 | 0.43 | 0.08–0.26 | 0.26 |
Gross national income | ||||||||||||||||||||
High income (≥12,276) per capita in USD | 14 | ref | 9 | ref | 16 | ref | 7 | ref | ||||||||||||
Upper middle income (3,976–12,275) | 1 | 0.96 | 2.61 | 0.34–20.12 | 0.33 | 1 | −1.26 | 0.28 | 0.01–6.41 | 0.39 | 7 | −1.02 | 0.36 | 0.07–1.80 | 0.20 | 0 | — | |||
Lower middle income (1,006–3,975) | 1 | −0.06 | 0.94 | 0.11–7.75 | 0.95 | 4 | 0.24 | 1.27 | 0.12–13.54 | 0.83 | 1 | 4.60 | 99.78 | 6.26–39.49 | 0.03 | 1 | 0.99 | 2.69 | 0.53–13.67 | 0.19 |
Low income (≤1,005) | 0 | — | 0 | — | 0 | — | 1 | −2.02 | 0.13 | 0.06–0.32 | 0.00 | |||||||||
Antibiotics | ||||||||||||||||||||
None | 0 | 4 | ref | 4 | ref | 0 | ||||||||||||||
Some | 13 | ref | 5 | 0.26 | 1.29 | 0.08–19.72 | 0.84 | 7 | 1.42 | 4.15 | 0.27–63.06 | 0.29 | 7 | ref | ||||||
Unknown | 3 | −0.58 | 0.56 | 1.41–20.12 | 0.20 | 5 | −0.56 | 0.57 | 0.05–7.10 | 0.64 | 13 | 0.44 | 1.56 | 0.13–18.63 | 0.71 | 2 | −1.19 | 0.30 | 0.07–1.42 | 0.11 |
Gestational age | ||||||||||||||||||||
All | 8 | ref | 12 | 24 | — | 5 | ref | |||||||||||||
Premature | 8 | −0.72 | 0.49 | 0.99–20.12 | 0.05 | 2 | −0.61 | 0.54 | 0.03–10.29 | 0.66 | 0 | 4 | 0.12 | 1.13 | 0.18–6.98 | 0.88 | ||||
WHO Region | ||||||||||||||||||||
Americas | 6 | ref | 5 | ref | 3 | ref | 3 | ref | ||||||||||||
Africa | 0 | — | 0 | — | 1 | −2.09 | 0.12 | 0.00–7.55 | 0.30 | 1 | −2.19 | 0.11 | 0.03–0.37 | 0.01 | ||||||
Eastern Mediterranean | 0 | — | 1 | −0.51 | 0.60 | 0.00–96.20 | 0.83 | 2 | 3.29 | 26.91 | 0.60–1212.80 | 0.09 | 0 | — | ||||||
Europe | 6 | −0.51 | 0.60 | 0.24–1.49 | 0.25 | 3 | 0.43 | 1.54 | 0.07–35.60 | 0.76 | 14 | −0.12 | 0.89 | 0.08–9.83 | 0.92 | 3 | −0.33 | 0.72 | 0.24–2.16 | 0.45 |
South east Asia | 1 | −0.32 | 0.72 | 0.08–6.49 | 0.75 | 3 | 0.60 | 1.82 | 0.07–50.27 | 0.69 | 0 | — | 1 | 0.81 | 2.26 | 0.32–15.96 | 0.31 | |||
Western Pacific | 3 | −0.49 | 0.61 | 0.16–2.36 | 0.44 | 2 | −0.81 | 0.45 | 0.02–10.30 | 0.58 | 4 | −1.60 | 0.20 | 0.01–3.23 | 0.24 | 1 | −0.39 | 0.67 | 0.20–2.26 | 0.42 |
Regression coefficient from metaregression.