Table 1.
Patients and samples*
| Patient group | Diagnosis | Age, years | Sex | Disease duration, years | Age of onset, years | No. of biopsies analyzed, all negative for dysplasia |
|||
|---|---|---|---|---|---|---|---|---|---|
| Set 1 | |||||||||
| non-UC | Constipation | 20 | F | — | — | 1 | |||
| non-UC | Constipation | 26 | F | — | — | 1 | |||
| non-UC | Diverticulitis | 36 | M | — | — | 1 | |||
| non-UC | Diverticulitis | 43 | M | — | — | 1 | |||
| non-UC | Diverticulitis | 50 | M | — | — | 1 | |||
| UC NP | Negative | 20 | M | 12 | 8 | 4 | |||
| UC NP | Negative | 33 | F | 8 | 25 | 2 | |||
| UC NP | Negative | 43 | M | 13 | 30 | 2 | |||
| UC NP | Negative | 46 | F | 17 | 29 | 3 | |||
| UC NP | Negative | 51 | F | 20 | 31 | 3 | |||
| UC NP | Negative | 52 | F | 18 | 16 | 3 | |||
| UC NP | Negative | 57 | F | 8 | 49 | 4 | |||
| UC NP | Negative | 60 | M | 44 | 16 | 2 | |||
| UC NP | Negative | 77 | F | 24 | 53 | 2 | |||
| UC P | Cancer | 35 | M | 14 | 21 | 4 | |||
| UC P | Cancer | 40 | M | 20 | 20 | 4 | |||
| UC P | HGD | 47 | M | 20 | 27 | 4 | |||
| UC P | Cancer | 47 | F | 14 | 33 | 2 | |||
| UC P | HGD | 51 | M | 15 | 36 | 2 | |||
| UC P | HGD | 54 | M | 20 | 34 | 4 | |||
| UC P | Cancer | 61 | M | 8 | 53 | 3 | |||
| UC P | Cancer | 63 | M | >8 | NA | 3 | |||
| UC P | Cancer | 70 | F | 52 | 18 | 3 | |||
| Total | 59 | ||||||||
| No. of biopsies analyzed, highest dysplastic grade | |||||||||
| Negative | LGD | HGD | Cancer | ||||||
| Set 2 | |||||||||
| UC P | HGD | 48 | M | 10 | 38 | 3 | 1 | 1 | |
| UC P | HGD | 58 | M | 29 | 29 | 5 | 1 | 1 | |
| UC P | Cancer | 31 | M | 4 | 27 | 11 | 1 | NA | 2 |
| UC P | Cancer | 33 | F | 22 | 11 | 1 | 1 | 1 | 3 |
| UC P | Cancer | 36 | M | 8 | 28 | 3 | 1 | 1 | 1 |
| UC P | Cancer | 51 | F | 13 | 38 | 4 | 1 | 2 | 2 |
| Total | 27 | 6 | 6 | 8 | |||||
* F = female; HGD = high-grade dysplasia; LGD = low-grade dysplasia; M = male; NA = not available; NP = nonprogressor; P = progressor; UC = ulcerative colitis.