Table 3. Inflammation under the control of Per2 during myocardial ischemia and reperfusion.

Inflammatory ‘Per2 genes’ I30R60	Fold change [Exp. Value]
Resistin-like molecule-beta	8.02
CCL3L1/CCL3L3	7.855
Metalloproteinase-8	5.05
Tumor Necrosis Factor	4.286
Immunoresponsive gene 1	4
Gadd45beta	3.9
S100A8/A9	3.919
IL1A interleukin 1, alpha	2.991
Interleukin 36, gamma	2.718
Triggering receptor expressed on myeloid cells 1	2.386
Toll-like receptor 2	2.212
Interleukin 17 receptor A	2.2
IL1R1 interleukin 1 receptor, type I	2.112

Shown are the top genes accounting for the identification of a dominant pro inflammatory program when analyzing genes that are only regulated in Per2^−/− mice using 30 minutes of ischemia and 60 minutes of reperfusion. Given are the expression values (fold change) obtained by Ingenuity pathway analysis. I30R60  = 30 minutes of ischemia and 60 minutes of reperfusion.