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. 2013 Aug 20;8(8):e71850. doi: 10.1371/journal.pone.0071850

Figure 7. GFP lamin A Q432X aggregates displace chromatin and sequester SREBP1.

Figure 7

COS7 cells transiently expressing GFP lamin A Q432X were stained with DAPI (A–A) and SREBP1 and DAPI (B–B). (A) At sides of strong aggregates the DAPI staining showed gaps (A, arrow). (B) Endogenous SRBP1 was sequestered into strong aggregates (B, arrow), rather than into smaller aggregates (B, thin arrow). Scale Bar: 10 µm.